12th house lord in 1st or ascendant 
The person may have weak constitution and lack vitality. Health may not be good. Endeavours undertaken may not yield much success. Phlegmatic ailments such as breathing problems and lung disorders may affect the health. The person may have little confidence or low self-esteem. Happiness in conjugal life is not well indicated. He may be of spiritual nature.

12th lord in 2nd house 
The person may be religious, tactful and sweet of speech. Expenses on auspicious deeds are indicated. He would be endowed with happiness. On the contrary, if 12th lord is afflicted, he may use foul language and may indulge in gossips and quarrelling. This signature disturbs the happiness in domestic life. Expenses are high.

12th lord in 3rd house 
This signature indicates the person is highly individualistic and may possess a strong sense of intuition. He or she would be steadfast and triumphant in accomplishments. He may be self- centred and efforts may not bring success if 12th lord is weak. He may be devoid of fraternal bliss. This is not a good signature for siblings.

12th lord in 4th house 
This signature is favourable for gaining education in foreign land as well as for foreign residence. There may be many changes of residence. In case there is association of a malefic planet, the native may incur losses in respect of land, conveyances and houses. In extreme cases, he may suffer constant harassment from landlord.

12th lord in 5th house 
The astrological signature is indicative of little happiness from children. This signature denotes little peace of mind. The native may suffer from tensions. Education may be disturbed. Success in speculative activities is not well indicated. It is bad for matters related to love.

12th lord in 6th house 
This signature is favourable for gaining success in matters related to litigation also. Trik lord in 6th house gives rise to harsha yoga, which is favourable for gaining material wealth if there is association of benefic planets. The person may be happy, prosperous and enjoys long life as well as comforts.

12th lord in 7th house 
This signature may indicate spouse from a different cast and creed. There may be less conjugal happiness. The native may be weak in health and strength. He may not be very well educated. He may associate himself with the world of spiritualism in later life.

12th lord in 8th house: 
The placement of Moksha lord in Moksha house indicates strong spiritual nature. The native may have interest in occult subjects. The person may get gains through legacies and enjoys comfortable life. However, there may not be much success in life due to lack of resources. Longevity may be less.

12th house lord in 9th house: 
If 12th lord is strong, then the native may experience fortunes from/through father. There may be success in acquiring property in foreign land. The person will be honest, generous and large hearted. In case, there is association of a malefic planet, there may be more concern about achieving selfish gains. The person may be inimical even to spouse, friends and preceptor. Luck may not favour and there may be no easy solutions to problems.

12th house lord 10th house 
This person may face troubles on account of superiors or government. He may be persecuted from persons in authority. So, he may experience difficulties in profession. Journeys may be tedious. He may not enjoy happiness or physical comforts from children. There may be expenditure through royal persons.

12th house lord in11th house 
The native may experience difficulties in fulfilling desires. There is an indication for financial losses. There may be few opportunities in life or few profits/gain. Relationship with eldest sibling may not be very harmonious. Debts or expenses on account of friends are a possibility also. This signature is unfavourable for investments and progeny bliss.

12th house lord in 12th house 
The person may spend money on religious and righteous purposes. There will be material comforts in lifetime. It is good for material prosperity but bad for health. The native may be restless and fond of travelling. However, this signature indicates unhappiness from progeny. This signature is good for people living away from homeland.